Jan 2015 – Dec 2019

Accelerating children's HIV treatment in Africa

Africa multiple countries (Kenya, Malawi, Tanzania, Zimbabwe)


Multiple countries – Africa

A global partnership to put 300,000 children living with HIV on life-saving treatment in nine countries in sub-Saharan Africa

$48,834,519 Grant Value

$1,052,544 evaluation budget



  • Rabin Martin

Download the new report on how ACT worked to change the lives of children living with HIV

Download the report now (PDF)

The $200 million initiative was co- funded by the US President’s Emergency Plan for AIDS Relief (PEPFAR) and CIFF. It aimed to dramatically increase the number of children on HIV treatment, and strengthen systems for paediatric HIV. 


In the first year of ACT, treatment coverage for children under 15 rose in all nine countries. Increases of more than 10% were seen in Kenya, Lesotho, Malawi, Tanzania, Zambia and Zimbabwe. 

At the Africa Leaders Summit in August 2014, CIFF and PEPFAR launched the Accelerating Children’s HIV/AIDS Treatment (ACT) Initiative in response to the fact that access to life-saving HIV drugs has persistently lagged behind for children.  The ACT initiative was a response to the challenges in paediatric HIV care and treatment in low resource settings, targeting technical and financial resources to selected high-burden countries.

By the end of September 2016, two years after the ACT initiative was announced, 561,610 children 19 years or under were on treatment. Between 2014 to 2016, the number of children under 14 years receiving treatment with support from PEPFAR and CIFF increased by 44% across the nine countries. As of September 2016, the ACT initiative had also enabled 16,431,861 children 19 years or under to have an HIV test with 468,149 found HIV positive. 

Click here to download a new report shares the promising practices and lessons learned from the Accelerating Children’s HIV/AIDS Treatment (ACT) Initiative.

Seeing real impact in Tanzania

In summer 2016, CIFF commissioned four case studies showing the impact the ACT initiative is seeing in Shinyanga, northern Tanzania. 

The cases, including two short films, focus on four core components of the ACT Initiative: testing, treatment, retention and adolescents.

You can watch this short film, click here to access or download all the case studies.

Evaluating the Sustainability of CIFF’s Investments in ACT 

CIFF commissioned Rabin Martin to conduct an evaluation of the sustainability of CIFF’s investments in the Accelerating Children’s HIV/AIDS Treatment (ACT) initiative in Kenya, Malawi, Tanzania, and Zimbabwe. The evaluation identified areas of strength and progress as well as gaps to be addressed in order to sustain gains made in paediatric and adolescent HIV in each of the four countries.  The sustainability framework developed to the guide the evaluation and the cross-country evaluation findings can be found via the following link: Rabin Martin ACT Report