May 2015 – Jun 2017
Operational and Implementation Research in Kenya
To test technical and implementation strategies for achieving STH transmission breakpoint
$877,387 Multi-Year Grant Value
Bill & Melinda Gates Foundation
This research in Kenya is at the forefront of new global efforts to pursue STH elimination through mass treatment of adults as well as children. One stream of work is testing whether STH transmission breakpoint can be achieved if an entire community—not only children—is treated with deworming drugs. Another stream of work is attempting to define the optimal way to distribute drugs to adults. Preliminary results show that high treatment coverage can be achieving using a centralised distribution point in a community, which is more cost-effective and efficient than door-to-door drug distribution. Results are expected by mid-2017 and will provide critical information on the technical and operational feasibility of broadening STH treatment to include adults.
This operational research will generate empirical evidence relating to strategies to break transmission for soil-transmitted helminths, validate and adjust ongoing modelling of STH transmission, inform and course-correct the Kenya and other national deworming programmes, and provide evidence to adjust World Health Organisation protocols accordingly, thereby influencing future generations of deworming programmes.